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News Physiol Sci 1: 100-103, 1986;
1548-9213/86 $5.00
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News in Physiological Sciences, Vol 1, 100-103, Copyright © 1986 by International Union of Physiological Sciences

ARTICLES

Does Availability of Inorganic Phosphate Regulate Cellular Oxidative Metabolism?

PC Brazy and LJ Mandel

Cells require inorganic phosphate for formation of ATP and a variety of other metabolic and transport functions. Studies of renal tubules indicate that availability of phosphate does regulate rates of oxidative metabolism and solute transport, that intracellular metabolic processes compete for inorganic phosphate, and that transepithelial phosphate transport provides inorganic phosphate for use within the cell.


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