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News Physiol Sci 1: 92-95, 1986;
1548-9213/86 $5.00
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News in Physiological Sciences, Vol 1, 92-95, Copyright © 1986 by International Union of Physiological Sciences

ARTICLES

Potassium Channels and Fluid Secretion

OH Peterson

Fluid secretion from exocrine glands can be switched on and off with great precision. Recent patch-clamp recordings of single-channel currents in acinar cells reveals that neurotransmitters and hormones control the opening of K+ channels. However, fluid secretion is due to transport of Na+ and Cl-, and movement of these ions occurs only when K+ can be transported simultaneously. Thus, by controlling K+ channels, neurotransmitters or hormones regulate Na+ and Cl-secretion.




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