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News in Physiological Sciences, Vol 1, 156-160, Copyright © 1986 by International Union of Physiological Sciences
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MC Moore-Ede
The circadian pacemakers, which time the approximately 24-h cycle of sleep and wakefulness, resynchronize only slowly after an abrupt phase shift in environmental time cues. Consequently, we are not well equipped to cope with jet travel across multiple time zones or with rotating shift work schedules, neither of which was in the evolutionary experience of the human species. Recent studies of the human circadian system suggest some strategies to minimize the ill effects of jet lag and shift work.
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