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News Physiol Sci 1: 160-163, 1986;
1548-9213/86 $5.00
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News in Physiological Sciences, Vol 1, 160-163, Copyright © 1986 by International Union of Physiological Sciences

ARTICLES

Angiogenesis in Skletal Muscle

HW Burton and JA Faulkner

Capillary growth is rarely observed in normal adult skeletal muscle, but angiogenesis may occur after injury to a capillary bed or after endurance training or chronic electrical stimulation. Revascularization of ischemic muscle may arise as inward growth from surrounding vascularized tissue, as outward growth from endothelial cells in ischemic muscle, or a combination of the two processes. A regenerated vascular bed shows diminished response to vasoactive agents and impaired regulation of blood flow during contractions.




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