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News Physiol Sci 10: 12-17, 1995;
1548-9213/95 $5.00
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News in Physiological Sciences, Vol 10, 12-17, Copyright © 1995 by International Union of Physiological Sciences

ARTICLES

Water Channels in Renal and Nonrenal Tissues

I Sabolic and D Brown

A family of structurally similar channel-forming membrane glycoproteins, termed water channels or aquaporins, accounts for the constitutive as well as vasopressin-regulated water permeability in respective epithelia. Heterogeneity of aquaporins provides a molecular basis for some genetic diseases and treatment of certain diseases with disturbances in water homeostasis.


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