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News in Physiological Sciences, Vol 10, 71-76, Copyright © 1995 by International Union of Physiological Sciences
ARTICLES |
M Joels and ER de Kloet
Adrenal corticosteroid hormones reach many organs including the brain where they exert persistent actions on neuronal excitability. Normally, steroid actions will maintain the integrity of neuronal networks, yet chronically decreased or enhanced corticosteroid levels can disrupt networks and enhance susceptibility to neurodegeneration.
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C. M. Coussens, D. S. Kerr, and W. C. Abraham Glucocorticoid Receptor Activation Lowers the Threshold for NMDA-Receptor-Dependent Homosynaptic Long-Term Depression in the Hippocampus Through Activation of Voltage-Dependent Calcium Channels J Neurophysiol, July 1, 1997; 78(1): 1 - 9. [Abstract] [Full Text] [PDF] |
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