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News Physiol Sci 10: 77-81, 1995;
1548-9213/95 $5.00
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News in Physiological Sciences, Vol 10, 77-81, Copyright © 1995 by International Union of Physiological Sciences

ARTICLES

Renal Proximal Tubule Response to Acid

RJ Alpern, Y Yamaji, M Amemiya, A Cano, PA Preisig, RT Miller and OW Moe

Changes in dietary acid and blood pH lead to adaptations in key enzymes and transport proteins of the renal proximal tubule that tend to return blood pH to normal. The mechanisms responsible, as well as acid-regulated signaling pathways that may effect these responses, are reviewed.




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