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News Physiol Sci 10: 117-122, 1995;
1548-9213/95 $5.00
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News in Physiological Sciences, Vol 10, 117-122, Copyright © 1995 by International Union of Physiological Sciences

ARTICLES

Molecular Mechanisms of Mural Thrombosis Under Dynamic Flow Conditions

JM Ross and LV McIntire

Mural adhesion and aggregation of blood platelets are crucial for hemostasis but in pathological situations can lead to myocardial infarction and stroke. The specific platelet surface receptors employed are determined by the local fluid dynamic conditions and extracellular matrix components exposed at the site of a vascular wound.




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