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News Physiol Sci 10: 129-133, 1995;
1548-9213/95 $5.00
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News in Physiological Sciences, Vol 10, 129-133, Copyright © 1995 by International Union of Physiological Sciences

ARTICLES

The Surface of the Heart Leaks Oxygen

DS Loiselle, JHGM van Beek, DA Mawson and PJ Hunter

The rate of oxygen consumption of the heart is classically measured using the Fick principle. Uncritical application of this principle can cause errors of measurement, particularly when estimating cardiac basal metabolic rate. Consideration of these errors leads to a model that supports modern notions of oxygen exchange in perfused tissue.




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