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News Physiol Sci 10: 171-176, 1995;
1548-9213/95 $5.00
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News in Physiological Sciences, Vol 10, 171-176, Copyright © 1995 by International Union of Physiological Sciences

ARTICLES

Annexins: Novel Ca2+-Dependent Regulators of Membrane Function

MA Kaetzel and JR Dedman

The annexins are a family of Ca2+-dependent membrane binding proteins that have been shown to regulate ion conductances, aggregate vesicles and the cytoskeleton, inhibit phospholipase A2, and inhibit blood coagulation. The annexins represent a unique mechanism of cellular regulation by modifying membrane functions in a Ca2+-dependent manner.


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