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News Physiol Sci 10: 265-273, 1995;
1548-9213/95 $5.00
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News in Physiological Sciences, Vol 10, 265-273, Copyright © 1995 by International Union of Physiological Sciences

ARTICLES

Functional Properties of Human b2-Adrenergic Receptor Polymorphisms

S Liggett

The same b2-adrenergic receptor is not expressed throughout the human population;there are at least six different forms of the receptor due to genetic polymorphisms within the coding block of the receptor gene. Site-directed mutagenesis and recombinant expression have shown that some of these variants have distinct pharmacological and biochemical phenotypes.


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