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News in Physiological Sciences, Vol 11, 1-7, Copyright © 1996 by International Union of Physiological Sciences
ARTICLES |
DM Warshaw
Muscular contraction is powered by myosin, a molecular motor, that derives its energy from hydrolysis of ATP as it interacts with actin. With the development of the in vitro motility assay, molecular events that couple ATP hydrolysis to mechanical work can be probed at the level of a single myosin molecular motor.
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E. P. Debold, J. P. Schmitt, J. B. Patlak, S. E. Beck, J. R. Moore, J. G. Seidman, C. Seidman, and D. M. Warshaw Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse {alpha}-cardiac myosin in the laser trap assay Am J Physiol Heart Circ Physiol, July 1, 2007; 293(1): H284 - H291. [Abstract] [Full Text] [PDF] |
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J. P. Schmitt, E. P. Debold, F. Ahmad, A. Armstrong, A. Frederico, D. A. Conner, U. Mende, M. J. Lohse, D. Warshaw, C. E. Seidman, et al. Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function PNAS, September 26, 2006; 103(39): 14525 - 14530. [Abstract] [Full Text] [PDF] |
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N. R. Alpert, C. Brosseau, A. Federico, M. Krenz, J. Robbins, and D. M. Warshaw Molecular mechanics of mouse cardiac myosin isoforms Am J Physiol Heart Circ Physiol, October 1, 2002; 283(4): H1446 - H1454. [Abstract] [Full Text] [PDF] |
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C. COIRAULT, F. LAMBERT, J.-C. POURNY, and Y. LECARPENTIER Velocity of Actomyosin Sliding in Vitro Is Reduced in Dystrophic Mouse Diaphragm Am. J. Respir. Crit. Care Med., January 15, 2002; 165(2): 250 - 253. [Abstract] [Full Text] [PDF] |
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C. Reggiani, R. Bottinelli, and G. J. M. Stienen Sarcomeric Myosin Isoforms: Fine Tuning of a Molecular Motor Physiology, February 1, 2000; 15(1): 26 - 33. [Abstract] [Full Text] [PDF] |
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C. Perreault-Micale, A. D. Shushan, and L. M. Coluccio Truncation of a Mammalian Myosin I Results in Loss of Ca2+-sensitive Motility J. Biol. Chem., July 7, 2000; 275(28): 21618 - 21623. [Abstract] [Full Text] [PDF] |
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D. Stamenovic, S. M. Mijailovich, I. M. Tolic-Norrelykke, J. Chen, and N. Wang Cell prestress. II. Contribution of microtubules Am J Physiol Cell Physiol, March 1, 2002; 282(3): C617 - C624. [Abstract] [Full Text] [PDF] |
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