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News Physiol Sci 11: 1-7, 1996;
1548-9213/96 $5.00
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News in Physiological Sciences, Vol 11, 1-7, Copyright © 1996 by International Union of Physiological Sciences


ARTICLES

The In Vitro Motility Assay: A Window Into the Myosin Molecular Motor

DM Warshaw

Muscular contraction is powered by myosin, a molecular motor, that derives its energy from hydrolysis of ATP as it interacts with actin. With the development of the in vitro motility assay, molecular events that couple ATP hydrolysis to mechanical work can be probed at the level of a single myosin molecular motor.


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