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News in Physiological Sciences, Vol 11, 24-30, Copyright © 1996 by International Union of Physiological Sciences
ARTICLES |
T Clausen
In skeletal muscle, activity and capacity of the Na+ -K+ pump are controlled by several hormones, contractile activity, growth, and nutrition. Acute or chronic reduction of the pump capacity inhibits contractile performance. Conversely, acute hormonal stimulation of the Na+ -K+ pump leads to marked, rapid force recovery in muscles where contractility is suppressed by high extracellular K+.
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