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News Physiol Sci 11: 48-52, 1996;
1548-9213/96 $5.00
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News in Physiological Sciences, Vol 11, 48-52, Copyright © 1996 by International Union of Physiological Sciences

ARTICLES

Intrarenal Alterations in Experimental Liver Cirrhosis

M Atucha and G-E Joaquin

In liver cirrhosis, renal reabsorption of water and sodium precedes ascites formation. Reduced renal excretory rates can be found in the absence of changes in plasma levels of main systemic hormones. It is possible that intrarenal elevations of antinatriuretic systems participate in retention of water and sodium in early cirrhosis.


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