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News Physiol Sci 11: 103-107, 1996;
1548-9213/96 $5.00
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News in Physiological Sciences, Vol 11, 103-107, Copyright © 1996 by International Union of Physiological Sciences

ARTICLES

Hepatorenal and Hepatointestinal Reflexes in Sodium Homeostasis

H Hosomi and H Morita

Hepatorenal and hepatointestinal reflexes with receptors in the hepatoportal region transduce portal plasma Na+ concentration into hepatic afferent nerve activity and reflexively augment renal Na+ excretion and attenuate intestinal Na+ absorption before a measurable increase in systemic Na+ concentration. These reflexes contribute to Na+ homeostasis in a negative, "feedforward" fashion.


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