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News Physiol Sci 11: 126-133, 1996;
1548-9213/96 $5.00
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News in Physiological Sciences, Vol 11, 126-133, Copyright © 1996 by International Union of Physiological Sciences

ARTICLES

Activation and Supply of Channels and Pumps by Aldosterone

F Verrey and J Beron

Mineralocorticoid and glucocorticoid hormones stimulate sodium reabsorption across target epithelia by modulating the transcription rate of a cell-specific set of genes. Unidentified regulated gene products mediate an early activation of preexisting sodium channels and pumps. In a later phase, the supply of proteins belonging to the sodium-transport machinery is increased.


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