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News Physiol Sci 11: 223-228, 1996;
1548-9213/96 $5.00
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News in Physiological Sciences, Vol 11, 223-228, Copyright © 1996 by International Union of Physiological Sciences

ARTICLES

Activation of Different Opioid Systems by Muscle Activity and Exercise

P Hoffmann, IH Jonsdottir and P Thoren

Many positive effects of exercise have been ascribed to the exercise-induced activation of endogenous opioid systems. The hypothesis that different opioid peptides and receptors are involved in the cardiovascular, behavioral, and analgesic responses and that opioid-mediated effects of muscle exercise are triggered by activation of mechanosensitive muscle nerve afferents is reviewed.


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