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News Physiol Sci 12: 105-112, 1997;
1548-9213/97 $5.00
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News in Physiological Sciences, Vol 12, 105-112, Copyright © 1997 by International Union of Physiological Sciences


ARTICLES

Channelopathies: Their Contribution to Our Knowledge About Voltage-Gated Ion Channels

F Lehmann-Horn and R Rudel

Since 1990, many mutations in genes encoding voltage-dependent sodium, potassium, calcium, and chloride channels have been discovered to cause disorders of heart, skeletal muscle, brain, or kidney. Study of the defective gene products has furthered our knowledge not only of pathology but also of ion-channel function.


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