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News Physiol Sci 12: 219-225, 1997;
1548-9213/97 $5.00
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News in Physiological Sciences, Vol 12, 219-225, Copyright © 1997 by International Union of Physiological Sciences

ARTICLES

Endocytosis of Polypeptides in Rabbit Nasal Respiratory Mucosa

D Cremaschi, C Porta and R Ghirardelli

The nasal respiratory mucosa of the rabbit has a leaky epithelium actively transporting polypeptides by a specific transcytosis probably involved in sampling antigens. The transfer displays saturation kinetics and is abolished by metabolic inhibitors, actin filamet and microtubule disassemblers, inhibitors of vesicle fusion, and receptor recycling;it accepts polypeptide-covered but not uncovered nanoparticles.


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 J. Appl. Physiol.Home page
D. Cremaschi, S. Dossena, C. Porta, V. Rossi, and M. Pinza
Further analysis of transcytosis of free polypeptides and polypeptide-coated nanobeads in rabbit nasal mucosa
J Appl Physiol, July 1, 2001; 91(1): 211 - 217.
[Abstract] [Full Text] [PDF]


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