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News Physiol Sci 13: 53-57, 1998;
1548-9213/98 $5.00
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News in Physiological Sciences, Vol. 13, No. 2, 53-57, April 1998
© 1998 Int. Union Physiol. Sci./Am. Physiol. Soc.

From Genetically Altered Mice to Integrative Physiology

Max Gassmann and Thierry Hennet

M. Gassmann and T. Hennet are at the Institute of Physiology, University of Zürich-Irchel, CH-8057 Zürich, Switzerland.
Transgenic and gene-targeted mice permit the study of the function(s) of the single gene(s) in a whole organism, thereby relating molecular biology and integrative physiology. To demonstrate the potential of transgenic models, we present in this review some physiologically relevant information obtained from genetically engineered mice.




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