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News Physiol Sci 13: 63-69, 1998;
1548-9213/98 $5.00
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News in Physiological Sciences, Vol. 13, No. 2, 63-69, April 1998
© 1998 Int. Union Physiol. Sci./Am. Physiol. Soc.

Visual Pigments and Molecular Genetics of Color Blindness

J. K. Bowmaker

J. K. Bowmaker is in the Dept. of Visual Science, Institute of Ophthalmology, University College London, Bath St., London EC1V 9EL, UK.
Red/green color blindness, found in ~1 in 15 men, is caused by the expression of hybrid genes coding for visual pigments. Spectral information from site-directed mutagenesis and recombinant expression has led to the possibility of correlating individual genotypes with psychophysical measurements of the severity of the deficiency.






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