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Calcium Mobilization Systems During Neurogenesis

Masayuki Yamashita and Miho Sugioka

M. Yamashita and M. Sugioka are in the Dept. of Physiology, Osaka University Medical School, Yamadaoka 2-2, Suita 565, Osaka Japan.
Neuroepithelial cells have Ca²⁺ mobilization systems that are activated by acetylcholine via muscarinic receptors and by extracellular ATP via P_2U purinoceptors. The Ca²⁺ mobilization occurs during neurogenesis and diminishes in parallel with the declining of mitotic activities of the neuroepithelial cells. Capacitative Ca²⁺ influx also occurs with the Ca²⁺ mobilization.

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