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News Physiol Sci 13: 225-231, 1998;
1548-9213/98 $5.00
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News in Physiological Sciences, Vol. 13, No. 5, 225-231, October 1998
© 1998 Int. Union Physiol. Sci./Am. Physiol. Soc.

Two Subgroups of Gonadotropin Releasing Hormone Neurons Control Gonadotropin Secretion in Rats

Fukuko Kimura and Toshiya Funabashi

F. Kimura and T. Funabashi are in the Dept. of Physiology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan.
Two distinct subgroups of gonadotropin-releasing hormone (GnRH) neurons are involved in the control of luteinizing hormone secretion, at least in rats: one subgroup located in the mediobasal hypothalamus constitutes the GnRH pulse generator associated with opioid neurons, and the other located in the preoptic area constitutes the GnRH surge generator associated with {gamma}-aminobutyric acid neurons.




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