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H. J. Cooke is in the Dept. of Pharmacology, Ohio State Univ., 333 W. 10th Ave., Columbus, OH 43210, USA.
Neural reflex circuits within the submucosal plexus and axon reflexes via extrinsic primary afferents control chloride secretion by intestinal epithelial cells. The regulation of chloride secretion is a complex interplay between excitatory and inhibitory influences from neurotransmitters and chemical messengers released from epithelial, endocrine, and immune cells.
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