| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
A. Behrooz and F. Ismail-Beigi are in the Departments of Molecular Biology and Microbiology, Medicine, and Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106–4951, USA.
Glucose transport is acutely stimulated by hypoxia through enhanced GLUT-1 and GLUT-4 glucose transporter function. GLUT-1 expression is also stimulated by hypoxia or azide. Moreover, hypoxia per se, acting through hypoxia-inducible factor 1, enhances GLUT-1 transcription. GLUT-1 is the first gene whose transcription is dually stimulated in response to hypoxia and inhibition of oxidative phosphorylation.
This article has been cited by other articles:
|
|
 |
|
  A Y Isa, T H Ward, C M L West, N J Slevin, and J J Homer Hypoxia in head and neck cancer Br. J. Radiol., October 1, 2006; 79(946): 791 - 798. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. S. Barry, M. L. Davidsen, S. W. Limesand, H. L. Galan, J. E. Friedman, T. R. H. Regnault, and W. W. Hay Jr. Developmental Changes in Ovine Myocardial Glucose Transporters and Insulin Signaling Following Hyperthermia-Induced Intrauterine Fetal Growth Restriction. Experimental Biology and Medicine, May 1, 2006; 231(5): 566 - 575. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. S. Ullah, A. J. Davies, and A. P. Halestrap The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1{alpha}-dependent Mechanism J. Biol. Chem., April 7, 2006; 281(14): 9030 - 9037. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Zoll, E. Ponsot, S. Dufour, S. Doutreleau, R. Ventura-Clapier, M. Vogt, H. Hoppeler, R. Richard, and M. Fluck Exercise training in normobaric hypoxia in endurance runners. III. Muscular adjustments of selected gene transcripts J Appl Physiol, April 1, 2006; 100(4): 1258 - 1266. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. R. Hall, T. J. MacCormack, C. A. Barry, and W. R. Driedzic Sequence and expression of a constitutive, facilitated glucose transporter (GLUT1) in Atlantic cod Gadus morhua J. Exp. Biol., December 15, 2004; 207(26): 4697 - 4706. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Clow, K. J. Rodnick, T. J. MacCormack, and W. R. Driedzic The regulation and importance of glucose uptake in the isolated Atlantic cod heart: rate-limiting steps and effects of hypoxia J. Exp. Biol., May 1, 2004; 207(11): 1865 - 1874. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Heilig, F. Brosius, B. Siu, L. Concepcion, R. Mortensen, K. Heilig, M. Zhu, R. Weldon, G. Wu, and D. Conner Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress Am. J. Pathol., November 1, 2003; 163(5): 1873 - 1885. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Wright, J. J. Higgin, R. T. Raines, C. Steenbergen, and E. Murphy Activation of the Prolyl Hydroxylase Oxygen-sensor Results in Induction of GLUT1, Heme Oxygenase-1, and Nitric-oxide Synthase Proteins and Confers Protection from Metabolic Inhibition to Cardiomyocytes J. Biol. Chem., May 23, 2003; 278(22): 20235 - 20239. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. M. Comerford, M. O. Leonard, J. Karhausen, R. Carey, S. P. Colgan, and C. T. Taylor Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia PNAS, February 4, 2003; 100(3): 986 - 991. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
