| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
K. R. Spring is Chief, Section on Transport Physiology, Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892–1603, USA.
Our current understanding of the mechanism of fluid transport by epithelia relies upon mathematical models developed 30 years ago to explain the mechanism of solute-solvent coupling and the pathways taken by water across an epithelium. The validity of these models is reconsidered in light of recent findings, and it is concluded that a simple three-compartment model system is adequate to explain fluid absorption and secretion by epithelia.
This article has been cited by other articles:
|
|
 |
|
  R. Sturm and W. Hofmann A multi-compartment model for slow bronchial clearance of insoluble particles--extension of the ICRP human respiratory tract models Radiat Prot Dosimetry, July 1, 2006; 118(4): 384 - 394. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. M. Charron, M. G. Blanchard, and J.-Y. Lapointe Intracellular Hypertonicity Is Responsible for Water Flux Associated with Na+/Glucose Cotransport Biophys. J., May 15, 2006; 90(10): 3546 - 3554. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. R. Gawenis, K. T. Boyle, B. A. Palmer, N. M. Walker, and L. L. Clarke Lateral intercellular space volume as a determinant of CFTR-mediated anion secretion across small intestinal mucosa Am J Physiol Gastrointest Liver Physiol, June 1, 2004; 286(6): G1015 - G1023. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Tarran Regulation of Airway Surface Liquid Volume and Mucus Transport by Active Ion Transport Proceedings of the ATS, January 1, 2004; 1(1): 42 - 46. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Guo, S. D. Hillyard, and B. M. Fu A two-barrier compartment model for volume flow across amphibian skin Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2003; 285(6): R1384 - R1394. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. E. Morris, J. A. Wang, and V. S. Markin The Invagination of Excess Surface Area by Shrinking Neurons Biophys. J., July 1, 2003; 85(1): 223 - 235. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. R. Ramsey, T. J. Berndt, and F. G. Knox Indomethacin Blocks Enhanced Paracellular Backflux in Proximal Tubules J. Am. Soc. Nephrol., June 1, 2002; 13(6): 1449 - 1454. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K.-H. Lee, C. Finnigan-Bunick, J. Bahr, and D. Bunick Estrogen Regulation of Ion Transporter Messenger RNA Levels in Mouse Efferent Ductules Are Mediated Differentially Through Estrogen Receptor (ER) {alpha} and ER{beta} Biol Reprod, November 1, 2001; 65(5): 1534 - 1541. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Gallardo, L. P. Cid, C. P. Vio, and F. V. Sepulveda Aquaporin-2, a regulated water channel, is expressed in apical membranes of rat distal colon epithelium Am J Physiol Gastrointest Liver Physiol, September 1, 2001; 281(3): G856 - G863. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. G. Schultz Epithelial water absorption: Osmosis or cotransport? PNAS, March 27, 2001; 98(7): 3628 - 3630. [Full Text] [PDF]
|
|
|
|
|
|
P.-P. Duquette, P. Bissonnette, and J.-Y. Lapointe Local osmotic gradients drive the water flux associated with Na+/glucose cotransport PNAS, March 27, 2001; 98(7): 3796 - 3801. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A.-K. Meinild, D. D. F. Loo, A. M. Pajor, T. Zeuthen, and E. M. Wright Water transport by the renal Na+-dicarboxylate cotransporter Am J Physiol Renal Physiol, May 1, 2000; 278(5): F777 - F783. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Saparov, D. Kozono, U. Rothe, P. Agre, and P. Pohl Water and Ion Permeation of Aquaporin-1 in Planar Lipid Bilayers. MAJOR DIFFERENCES IN STRUCTURAL DETERMINANTS AND STOICHIOMETRY J. Biol. Chem., August 17, 2001; 276(34): 31515 - 31520. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
