HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Niggli, E. Search for Related Content PubMed PubMed Citation Articles by Niggli, E.

Ca²⁺ Sparks in Cardiac Muscle: Is There Life Without Them?

Ernst Niggli

E. Niggli is in the Department of Physiology, University of Bern, 3012 Bern, Switzerland (E-mail: niggli{at}pyl.unibe.ch; http://beam.to/calcium_quark).
The discovery of elementary Ca²⁺ signaling events, the Ca²⁺ sparks, has profoundly changed our view of cardiac Ca²⁺ signaling and, in particular, excitationcontraction coupling. In addition, a partial disruption of cardiac Ca²⁺ signaling may be important in clinical cardiac conditions such as congestive heart failure. Understanding cardiac diseases on the cellular and molecular levels may provide a key to new pharmacological strategies in the near future.

This article has been cited by other articles:

				K. Hillsley, J. L. Kenyon, and T. K. Smith Ryanodine-Sensitive Stores Regulate the Excitability of AH Neurons in the Myenteric Plexus of Guinea-Pig Ileum J Neurophysiol, December 1, 2000; 84(6): 2777 - 2785. [Abstract] [Full Text] [PDF]