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Z. Shao is in the Department of Molecular Physiology and Biological Physics of the University of Virginia, PO Box 10011, Charlottesville, VA 22906-0011, USA.
Atomic force microscopy (AFM) can generate high-resolution images of the surface of biological specimens and can also probe the interactions between and within single macromolecules. Thus isolated heterogeneous biological structures can be studied in submolecular detail with AFM.
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