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Sensorimotor Integration at the Dorsal Column Nuclei

Jorge Mariño, Luis Martinez and Antonio Canedo

J. Mariño and A. Canedo are in the Department of Physiology, Faculty of Medicine, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain; and L. Martinez is in the Laboratory of Neurobiology at Rockefeller University, 1230 York Ave., New York, NY 10021-6399.
Interaction among primary afferents, corticofugal fibers, and intrinsic elements allows for sensorimotor integration at the dorsal column nuclei. The interneurons permit the spatial localization, the recurrent collaterals synchronize the activity of projecting cells with overlapping receptive fields, and the corticofugal fibers induce a central zone of activity surrounded by a peripheral zone of inhibition.

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