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PTH and PTHrP: Similar Structures but Different Functions

K.-D. Schlüter

K.-D. Schlüter is at the Physiologisches Institut, Aulweg 129, D-35392 Giessen, Germany.
Parathyroid hormone and parathyroid hormone-related peptide are two structurally similar peptide hormones that exert mainly identical effects on classical target cells of parathyroid hormone but remarkable differences in their effects on other target cells. This review focuses on their functional differences and the mechanisms underlying these effects.

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