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Presynaptic Heterogeneity: Vive la difference

Julie K. Staple, Florence Morgenthaler and Stefan Catsicas

J. K. Staple, F. Morgenthaler, and S. Catsicas are in l’Institut de Biologie Cellulaire et de Morphologie, Lausanne, Switzerland.
Since individual synapses of the same neuron may have different molecular composition, an important question in neurobiology is how the properties of individual synapses are established and maintained. Recent technical advances allow assay of activity at individual synapses and investigation of the relationship between function and molecular composition at the synapse.

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