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Interface Properties of Circumventricular Organs in Salt and Fluid Balance

Eckhart Simon

E. Simon is Professor and Head of the Physiology Department at Max-Planck-Institute for Physiological and Clinical Research, William G. Kerckhoff-Institute, D-61231 Bad Nauheim, Germany.
The "sensory" circumventricular organs, with their leaky blood-brain barriers, permit contact between brain neurons and blood-borne molecules. Body fluid balance and cardiovascular control involve established interface functions of subfornical organs. Their recently identified target functions for hormones released during digestion suggest that they may coordinate fluid and food intake.

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