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News Physiol Sci 15: 67-71, 2000;
1548-9213/00 $5.00
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News in Physiological Sciences, Vol. 15, No. 2, 67-71, April 2000
© 2000 Int. Union Physiol. Sci./Am. Physiol. Soc.

Intracellular Virus Trafficking Reveals Physiological Characteristics of the Cytoskeleton

Robert P. Stidwill and Urs F. Greber

R. P. Stidwill and U. F. Greber are in the Department of Zoology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Virus particles that infect eukaryotic cells can take advantage of the cytoskeleton and associated motors to translocate through the cytoplasm. Depending on the virus, motor proteins are recruited or, alternatively, cytoskeletal elements are induced to polymerize onto viral structures. Here we review recent advances toward understanding the roles of the cytoskeleton in virus trafficking.




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