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The Time Course of Signaling at Central Glutamatergic Synapses

Peter Jonas

P. Jonas is in the Physiologisches Institut der Universität Freiburg, D-79104 Freiburg, Germany.
Glutamate is the main excitatory transmitter in the mammalian CNS, mediating fast synaptic transmission primarily by activation of AMPA-type glutamate receptor channels. Both synaptic structure and a cell-specific molecular switch in the AMPA receptor subunit expression are involved in the regulation of the synaptic signaling time course.

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