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News Physiol Sci 15: 107-113, 2000;
1548-9213/00 $5.00
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News in Physiological Sciences, Vol. 15, No. 3, 107-113, June 2000
© 2000 Int. Union Physiol. Sci./Am. Physiol. Soc.

Adhesion Molecules: The Path to a New Understanding of Acute Inflammation

Barbara Walzog and Peter Gaehtgens

B. Walzog and P. Gaehtgens are in the Department of Physiology, Freie Universität Berlin, Arnimallee 22, D-14195 Berlin, Germany.
About 100 years after the definition of the basic principles of inflammation, the identification of the underlying molecular mechanisms provides a new understanding of the inflammatory response. The specificity and diversity of the adhesion molecules involved in leukocyte extravasation account for the ordered leukocyte recruitment and activation in inflammation.




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