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News Physiol Sci 15: 171-175, 2000;
1548-9213/00 $5.00
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News in Physiological Sciences, Vol. 15, No. 4, 171-175, August 2000
© 2000 Int. Union Physiol. Sci./Am. Physiol. Soc.

Angiotensin II Receptor Physiology Using Gene Targeting

Michael I. Oliverio and Thomas M. Coffman

M. I. Oliverio and T. M. Coffman are at Duke University and Durham Veterans Affairs Medical Centers, Room 1100/Building 6, 508 Fulton Street, Durham, North Carolina, 27705.
The study of mice with targeted disruptions of angiotensin receptor genes has provided new insights into the roles of the individual receptor subtypes, i.e., AT1A, AT1B, and AT2, in growth, development, and the regulation of blood pressure.




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