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News Physiol Sci 15: 229-233, 2000;
1548-9213/00 $5.00
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News in Physiological Sciences, Vol. 15, No. 5, 229-233, October 2000
© 2000 Int. Union Physiol. Sci./Am. Physiol. Soc.

Role of Nitric Oxide in Buffering Short-Term Blood Pressure Fluctuations

Harald M. Stauss and Pontus B. Persson

H. M. Stauss is Privatdozent and P. B. Persson is Professor at the Department at Johannes-Müller-Institut für Physiologie, Humboldt-Universität, (Charite), Tucholskystrasse 2, 10117 Berlin, Germany.
Blood pressure instability may promote cardiovascular morbidity. Recent data suggest a role of nitric oxide in stabilizing arterial blood pressure. A rise in blood pressure enhances endothelial shear stress and nitric oxide release. The resulting vasodilation antagonizes the initial increase in blood pressure. This system can respond within 2–10 seconds.




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