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News Physiol Sci 15: 241-245, 2000;
1548-9213/00 $5.00
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News in Physiological Sciences, Vol. 15, No. 5, 241-245, October 2000
© 2000 Int. Union Physiol. Sci./Am. Physiol. Soc.

Stopping Exercise: Role of Pulmonary C Fibers and Inhibition Of Motoneurons

Simon C. Gandevia, Janet L. Taylor and Jane E. Butler

S. C. Gandevia, J. L. Taylor, and J. E. Butler are at the Prince of Wales Medical Research Institute and University of New South Wales, Sydney, 2031 Australia.
In animals, the J reflex evoked by pulmonary C fibers provides potent inhibition of limb muscles and would act to limit exercise. However, recent work shows that although activation of these fibers causes severe respiratory discomfort, it does not impair the output of limb motoneurons to voluntary, reflex, or locomotor drives in awake humans.






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