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News Physiol Sci 16: 29-33, 2001;
1548-9213/01 $5.00
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News in Physiological Sciences, Vol. 16, No. 1, 29-33, February 2001
© 2001 Int. Union Physiol. Sci./Am. Physiol. Soc.

Ion Channels and Transporters on the Move

Albrecht Schwab

A. Schwab is at the Physiologisches Institut, Röntgenring 9, D-97070 Würzburg, Germany.
Cell migration plays a crucial role in a variety of (patho)physiological processes such as immune defense, wound healing, and formation of tumor metastases. Detailed models have been developed to describe cytoskeletal mechanisms of migration. However, evidence is accumulating that the activity of ion channels and transporters is also required for optimal cell locomotion.




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