Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

News Physiol Sci 16: 157-160, 2001;
1548-9213/01 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (11)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Welbourne, T.
Right arrow Articles by Nissim, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Welbourne, T.
Right arrow Articles by Nissim, I.
News in Physiological Sciences, Vol. 16, No. 4, 157-160, August 2001
© 2001 Int. Union Physiol. Sci./Am. Physiol. Soc.

The Glutamine/Glutamate Couplet and Cellular Function

Tomas Welbourne1, Robert Routh2, Marc Yudkoff3 and Itzhak Nissim3

1 Departments of Molecular and Cellular Physiology and
2 Molecular and Cellular Pathology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130; and
3 Division of Child Development and Rehabilitation, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318
All cells require glutamine as a nitrogen donor as well as an energy source for cell-specific functions. Understanding how glutamine utilization is metered to these demands is fundamental to basic cell processes as well as to therapeutic manipulation of regulatory mechanisms. The regulatory role of the glutamine/glutamate couplet in cellular function is illustrated for acid-base homeostasis and for production of the extracellular matrix.




This article has been cited by other articles:


Home page
 Am. J. Physiol. Renal Physiol.Home page
M. Andratsch, E. Feifel, L. Taylor, M. O'Hayre, H. Schramek, N. P. Curthoys, and G. Gstraunthaler
TGF-beta signaling and its effect on glutaminase expression in LLC-PK1-FBPase+ cells
Am J Physiol Renal Physiol, September 1, 2007; 293(3): F846 - F853.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
T. Welbourne, E. Friday, R. Fowler, F. Turturro, and I. Nissim
Troglitazone acts by PPAR{gamma} and PPAR{gamma}-independent pathways on LLC-PK1-F+ acid-base metabolism
Am J Physiol Renal Physiol, January 1, 2004; 286(1): F100 - F110.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. L. O'Malley, Y.-J. I. Jong, Y. Gonchar, A. Burkhalter, and C. Romano
Activation of Metabotropic Glutamate Receptor mGlu5 on Nuclear Membranes Mediates Intranuclear Ca2+ Changes in Heterologous Cell Types and Neurons
J. Biol. Chem., July 18, 2003; 278(30): 28210 - 28219.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
G. Coates, I. Nissim, H. Battarbee, and T. Welbourne
Glitazones regulate glutamine metabolism by inducing a cellular acidosis in MDCK cells
Am J Physiol Endocrinol Metab, October 1, 2002; 283(4): E729 - E737.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
T. Welbourne, G. Su, G. Coates, R. Routh, K. McCarthy, and H. Battarbee
Troglitazone induces a cellular acidosis by inhibiting acid extrusion in cultured rat mesangial cells
Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2002; 282(6): R1600 - R1607.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
R. Routh, K. McCarthy, and T. Welbourne
Troglitazone inhibits glutamine metabolism in rat mesangial cells
Am J Physiol Endocrinol Metab, January 1, 2002; 282(1): E231 - E238.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online