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Wellcome Trust Cellular Physiology Research Unit, Department of Physiology, University College Cork, Ireland
Recent evidence points to protein kinase C isoforms as highly specific receptors for aldosterone and estradiol in epithelia. The end targets of the kinase activation are Na+/H+ exchange and K+ and Ca2+ channels. The physiological role of the nongenomic response is to increase electrolyte absorption and inhibit secretion in pluripotential epithelia.
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