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News Physiol Sci 16: 262-265, 2001;
1548-9213/01 $5.00
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News in Physiological Sciences, Vol. 16, No. 6, 262-265, December 2001
© 2001 Int. Union Physiol. Sci./Am. Physiol. Soc.

Renal Transplantation Studies in Genetic Hypertension

Olaf Grisk and Rainer Rettig

Department of Physiology, University of Greifswald, D-17487 Greifswald, Germany
Renal cross-transplantation experiments revealed that the kidney plays a key role in primary hypertension. Advanced animal breeding strategies leading to the generation of congenic and consomic rat strains combined with renal transplantation experiments will allow researchers to quantify the contribution of renal and extrarenal mechanisms to the development of genetic forms of hypertension.




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