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What Does the Brain Know About Blood Pressure?

Steven W. Mifflin

Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900
The integration of baroreceptor inputs within the central nervous system is modulated by a variety of inhibitory processes. It is proposed that, in hypertension, brain stem neurons adapt to increased excitatory baroreceptor inputs by increasing the efficacy of these inhibitory processes. Enhanced inhibition maintains some degree of reflex function in hypertension.

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