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News Physiol Sci 16: 292-296, 2001;
1548-9213/01 $5.00
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News in Physiological Sciences, Vol. 16, No. 6, 292-296, December 2001
© 2001 Int. Union Physiol. Sci./Am. Physiol. Soc.

Possible Genomic Consequence of Nongenomic Action of Glucocorticoids in Neural Cells

Yi-Zhang Chen1,2,4 and Jian Qiu3

1 Institute of Neuroscience,
2 Department of Neurobiology, and
3 Department of Physiology, Second Military Medical University, Shanghai 200433; and
4 Department of Neurobiology, Zhejiang University School of Medicine, Hangzhou 310031, China
The nongenomic, rapid effects of glucocorticoid activate multiple intracellular transduction pathways. This review proposes a possible genomic consequence of the nongenomic action of steroids. The genomic actions of hormonal steroids may be twofold: classic genomic and nongenomically induced genomic.




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