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News Physiol Sci 17: 105-109, 2002;
1548-9213/02 $5.00
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News in Physiological Sciences, Vol. 17, No. 3, 105-109, June 2002
© 2002 Int. Union Physiol. Sci./Am. Physiol. Soc.

Small Artery Remodeling and Significance in the Development of Hypertension

Michael J. Mulvany

Department of Pharmacology, University of Aarhus, 8000 Aarhus C, Denmark
The structure of the resistance vessels is altered (remodeled) in individuals with high blood pressure (essential hypertension). The structure is dependent not only on blood pressure but also on blood flow and hormonal environment. Vascular biology is providing increased knowledge of the mechanisms involved and thus contributing to our understanding of the pathophysiology of the disease.




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