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Cardiac Ca²⁺ Regulation and the Tuna Fish Sandwich

Stephen O’Neill

Unit of Cardiac Physiology, Department of Medicine, Manchester University, Manchester M13 9PT, UK
Following myocardial ischemia and reperfusion, there is a risk of fatal arrhythmias that result from damage to cellular Ca²⁺ homeostasis mechanisms. n-3 Polyunsaturated fatty acids seem to protect against these arrhythmias by mechanisms involving the sarcoplasmic reticulum and the sarcolemma.

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