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Metabolic Myopathy in Heart Failure

Renée Ventura-Clapier, Elvira De Sousa and Vladimir Veksler

U-446 INSERM, Cardiologie Cellulaire et Moléculaire, Université Paris-Sud, 92 296 Châtenay-Malabry, France
Heart failure is a syndrome that also affects the periphery. Exercise intolerance and early fatigue seem to be linked in part to intrinsic alterations of skeletal muscle with decreases in both the production of ATP by mitochondria and the transfer of energy through the phosphotransfer kinases.

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