Physiology BIOPAC complete lab solutions
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

News Physiol Sci 17: 231-234, 2002; doi:10.1152/nips.01402.2002
1548-9213/02 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (22)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hagenbuch, B.
Right arrow Articles by Meier, Peter. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hagenbuch, B.
Right arrow Articles by Meier, Peter. J.
News in Physiological Sciences, Vol. 17, No. 6, 231-234, December 2002
© 2002 Int. Union Physiol. Sci./Am. Physiol. Soc.

Transport of Xenobiotics Across the Blood-Brain Barrier

Bruno Hagenbuch, Bo Gao and Peter. J. Meier

Division of Clinical Pharmacology and Toxicology, Department of Medicine, University Hospital, CH-8091 Zurich, Switzerland
Distinct transport proteins regulate the movement of waste products and xenobiotics across the blood-brain barrier (BBB). Members of the drug transporter families MDR, MRP, and OATP have been identified in the BBB, and a detailed characterization of the involved proteins is now required to target drugs more efficiently to the brain.




This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
I. A. Elkiweri, Y. L. Zhang, U. Christians, K.-Y. Ng, M. C. Tissot van Patot, and T. K. Henthorn
Competitive Substrates for P-Glycoprotein and Organic Anion Protein Transporters Differentially Reduce Blood Organ Transport of Fentanyl and Loperamide: Pharmacokinetics and Pharmacodynamics in Sprague-Dawley Rats
Anesth. Analg., January 1, 2009; 108(1): 149 - 159.
[Abstract] [Full Text] [PDF]

Home page
 Hum Exp ToxicolHome page
H Nevala, T Ylikomi, and H Tahti
Evaluation of the selected barrier properties of retinal pigment epithelial cell line ARPE-19 for an in-vitro blood-brain barrier model
Human and Experimental Toxicology, October 1, 2008; 27(10): 741 - 749.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
W. Lee, H. Glaeser, L. H. Smith, R. L. Roberts, G. W. Moeckel, G. Gervasini, B. F. Leake, and R. B. Kim
Polymorphisms in Human Organic Anion-transporting Polypeptide 1A2 (OATP1A2): IMPLICATIONS FOR ALTERED DRUG DISPOSITION AND CENTRAL NERVOUS SYSTEM DRUG ENTRY
J. Biol. Chem., March 11, 2005; 280(10): 9610 - 9617.
[Abstract] [Full Text] [PDF]

Home page
 Drug Metab. Dispos.Home page
L. M. Augustine, R. J. Markelewicz Jr., K. Boekelheide, and N. J. Cherrington
XENOBIOTIC AND ENDOBIOTIC TRANSPORTER MRNA EXPRESSION IN THE BLOOD-TESTIS BARRIER
Drug Metab. Dispos., January 1, 2005; 33(1): 182 - 189.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
N. Mizuno, T. Niwa, Y. Yotsumoto, and Y. Sugiyama
Impact of Drug Transporter Studies on Drug Discovery and Development
Pharmacol. Rev., September 1, 2003; 55(3): 425 - 461.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online