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News Physiol Sci 17: 251-255, 2002; doi:10.1152/nips.01405.2002
1548-9213/02 $5.00
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News in Physiological Sciences, Vol. 17, No. 6, 251-255, December 2002
© 2002 Int. Union Physiol. Sci./Am. Physiol. Soc.

Indexes of NO Bioavailability in Human Blood

Thomas Lauer, Petra Kleinbongard and Malte Kelm

Klinik für Kardiologie, Pneumologie, und Angiologie, Heinrich-Heine-Universität Düsseldorf, D-40225 Düsseldorf, Germany
Disturbances of nitric oxide (NO) bioavailability may play a key role in vascular dysfunction and in the development of atherosclerotic lesions. Thus assessment of a reduced NO bioavailability in human circulation is of particular interest. Here we summarize potential biomarkers of NO availability in human blood and critically discuss their respective significance and application fields.




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