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News Physiol Sci 18: 23-28, 2003; doi:10.1152/nips.01406.2002
1548-9213/03 $5.00
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News in Physiological Sciences, Vol. 18, No. 1, 23-28, February 2003
© 2003 Int. Union Physiol. Sci./Am. Physiol. Soc.

Genesis and Control of the Respiratory Rhythm in Adult Mammals

Gérard Hilaire1 and Rosario Pásaro2

1 Biologie des Rythmes et du Développement, Centre National de la Recherche Scientifique, Groupe d’Etude des Réseaux Moteurs, 13009 Marseille, France; and
2 Faculty of Biology, Department of Physiology and Zoology, University of Seville, 41012 Sevilla, Spain
The neural mechanisms responsible for respiratory rhythmogenesis in mammals were studied first in vivo in adults and subsequently in vitro in neonates. In vitro data have suggested that the pacemaker neurons are the kernel of the respiratory network. These data are reviewed, and their relevance to adults is discussed.






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